解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Two-day-old rats were pretreated with 50 mg/kg of capsaicin. After 3--4 months, specific binding of [3H]muscimol and [3H]strychnine was measured in membrane preparations from dorsal spinal cord. A 20-30% decrease of the number of [3H]muscimol binding sites was observed after capsaicin treatment. In contrast, [3H]stryc...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90160-2
更新日期:1980-12-08 00:00:00
abstract::Previous studies have shown behavioral changes in pre- and postnatal rats exposed to morphine before and during gestation. The present study has attempted to discover morphological correlates of these changes in the fetal rat spinal cord. Pregnant Wistar rats were injected subcutaneously on days 12-18 of gestation wit...
journal_title:Brain research
pub_type: 杂志文章
doi:
更新日期:1980-11-24 00:00:00
abstract::Intracerebroventricular (ICV) infusions of 2-deoxy-D-glucose (2-DG) elicited hyperglycemia and increased feeding at short latencies. If access to food was prevented for 6 h post-2-DG infusion, when blood glucose levels were normal and brain 2-DG concentrations were virtually zero, the rats still ate significantly more...
journal_title:Brain research
pub_type: 杂志文章
doi:
更新日期:1980-11-24 00:00:00
abstract::Thyrotropin-releasing hormone (TRH) immunoreactivity in rat tissue was assayed using a new reversed-phase, ion-pair, high-pressure liquid chromatography (HPLC) method for separating TRH from its analogs. Virtually all of the TRH immunoreactivity in hypothalamus, brain stem, preoptic area, septum, striatum, frontal cor...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91036-7
更新日期:1980-11-17 00:00:00
abstract::A small, unilateral, penetrating wound was placed in the dorsolateral portion of the lumbosacral spinal cord in immature rats. Although this wound did not extend into the central canal area, some cells forming the walls of this canal underwent proliferative activity as demonstrated by [3H]thymidine autoradiography. Th...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90783-0
更新日期:1980-11-10 00:00:00
abstract::Alpha-bungarotoxin binding sites in chick retina from 12 days in ovo to hatching, were visualized at the ultrastructural level by use of a 1:1 conjugate of horseradish peroxidase with alpha-bungarotoxin. At all stages binding sites in the inner plexiform layer were localized in synapses, predominantly on or near the p...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90774-x
更新日期:1980-11-10 00:00:00
abstract::Using cervical sympathectomized and immobilized rabbits, the relationship between the luminance intensity and the magnitude of the response in pupillo-constrictor units of the ciliary nerve was investigated. It was revealed that the intensity--response relationship of the units closely resembled that of retinal recept...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90787-8
更新日期:1980-11-10 00:00:00
abstract::Respiratory neurons were recorded with microelectrodes in the medullary dorsal respiratory group of pentobarbital-anesthetized cats. The animals were ventilated with a phrenic-driven servorespirator that allowed manipulation of phasic volume feedback. By increasing or decreasing the gain of the servorespirator, graded...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90924-5
更新日期:1980-11-03 00:00:00
abstract::Previous studies have shown that muscarinic cholinergic agonists bind to 3 distinct receptor sites in brain, each being distinguished by their affinity for the agonists. Antagonists, on the other hand, bind to these sites with the same high affinity. The relative concentrations of the two high and the low affinity ago...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91089-6
更新日期:1980-10-27 00:00:00
abstract::Electrical stimulation in the dorsal acoustic stria (DAS) and the posterior and dorsal part of the ventral cochlear nucleus (VCN) was used to identify the response properties of efferent axons from the dorsal cochlear nucleus (DCN) in unanesthetized, decerebrate cats. Responses recorded in the DCN of this preparation ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91091-4
更新日期:1980-10-27 00:00:00
abstract::Nerve growth factor (NGF) transported intraaxonally from the adrenergic nerve terminals in the iris to the cell bodies in the superior cervical ganglion resulted in an increase in the activity of the enzyme ornithine decarboxylase in the ganglion. This occurred in both six-day-old and adult rats with the relative effe...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91092-6
更新日期:1980-10-27 00:00:00
abstract::Neuronal activity in the nucleus parabrachialis medialis (NPBM) was examined in unanesthetized, unrestrained cats during each sleep-waking state. Discharge related to the cardiac cycle was assessed by calculating cross-correlation functions between neuronal and cardiac events (using the peak of the EKG 'R' wave as a r...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90696-4
更新日期:1980-10-20 00:00:00
abstract::Lithium is detected in the mouse brain with the aid of a (n,alpha) nuclear reaction. The resolving power is of a few micron. The detection efficiency is estimated in a first series of experiments with brain sections of progressively increasing thickness. This allows us to make the microlocation of lithium in the brain...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90239-5
更新日期:1980-10-13 00:00:00
abstract::Using psychophysical techniques, the ability of human subjects to discriminate the velocity of brush movement across the glabrous skin of the hand was determined. The same stimulus was then used in a series of neurophysiological experiments designed to determine the ability of neurons in the primary somatosensory cort...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90746-5
更新日期:1980-10-06 00:00:00
abstract::Pharmacological studies using an in vitro model system were carried out to determine if naloxone, an opiate receptor antagonist, could have effects on neuronal membranes which were unrelated to its action as an opiate receptor antagonist. Intracellular recordings were made from cultured mammalian spinal cord neurons. ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90747-7
更新日期:1980-10-06 00:00:00
abstract::A series of experiments were performed to study the effects of learning upon proteins in the split-brain pigeon. With this preparation, one side of the brain was trained in a color discrimination task while the other side served as a naive control. Proteins from both sides of the brain were separated by one- and two-d...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90349-2
更新日期:1980-09-29 00:00:00
abstract::Unanesthetized adult male rats with indwelling right atrial cannulae were used in the majority of experiments. Morphine (MOR, 3.0 mg/kg) caused a large but transient increase in both GH and PRL levels, which could be prevented with naloxone. Disruption of central noradrenergic function with diethyldithiocarbamate (400...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91130-0
更新日期:1980-09-22 00:00:00
abstract::One model useful for demonstrating axonal regeneration in the central nervous system is that in which peripheral tissue, particularly the iris, is implanted into the brain or spinal cord. The aim of the present study was to establish the origin of some of the regenerating fibers by the use of an autoradiograhic tracin...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91121-x
更新日期:1980-09-22 00:00:00
abstract::Finger representation on the first somatosensory cortex was mapped in conscious monkeys by single-unit recording. While representation was somatotopic in area 3, this was not the case in area 2, where the representation of different fingers overlapped. Our results indicate that area 2 is not a pure replica of the rece...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91139-7
更新日期:1980-09-22 00:00:00
abstract::The accumulation of acid-labile CO2 was measured in the rat brain at early times after exposure to 30% CO2 in oxygen. In particular, the effect on CO2 accumulation of inhibiting brain carbonic anhydrase with acetazolamide was studied. For 57 rats, a rat head perfusion technique was used which permits control and rapid...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90443-6
更新日期:1980-09-15 00:00:00
abstract::Unilateral injections of 6-hydroxydopamine into the lateral hypothalamus or ventral tegmental area that damage extensively the mesotelencephalic dopaminergic projection result in significant hemispheric asymmetries in autoradiographic labeling after [14C]2-deoxy-D-glucose (2DG) administration. The incorporation of thi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90442-4
更新日期:1980-09-15 00:00:00
abstract::An experiment was performed in order to determine the role of the amygdala and surrounding cortex in quiet biting attack elicited from electrical stimulation of the hypothalamus. Stimulation of basal, cortical, and anterior amygdala as well as pyriform cortex and parahippocampal gyrus resulted in a suppression of the ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90433-3
更新日期:1980-09-15 00:00:00
abstract::Paranodal glial loops (lateral belt cytoplasm) of myelinated CNS and PNS fibres contain tubules of agranular reticulum, as well as microtubules, wound spirally around the axon. Similar agranular elements run circumferentially in the expanded rims of sheet-like astrocytic processes encapsulating thalamic synaptic glome...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90414-x
更新日期:1980-09-08 00:00:00
abstract::The activities of tyrosine hydroxylase and dopamine-beta-hydroxylase were measured in the medial basal hypothalamus and remaining hyothalamic tissue of female rats at various times during diestrus 2, proestrus and estrus. Tyrosine hydroxylase activity in the medial basal hypothalamus was significantly lower at 12.00 h...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90407-2
更新日期:1980-09-08 00:00:00
abstract::Radioautography was used to study the intraneuronal distribution of [3H]-serotonin (5-HT) and/or its derivatives selectively taken up by the olfactory bulb (OB) serotonergic terminals and subsequently transported to their parent cell bodies in the midbrain raphe nuclei. This was done 24 h after injection of [3H]5-HT i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90405-9
更新日期:1980-09-08 00:00:00
abstract::The effects of intraspinal microinjectins of morphine (10 microgram) and methionine-enkephalin (Met-enkephalin) (5 microgram) on the C-fiber and polysynaptic reflexes in the acute decerebrate low spinal cat were investigated. Microinjected into the dorsal horn, morphine and Met-enkephalin depressed the nociceptive C-f...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90409-6
更新日期:1980-09-08 00:00:00
abstract::The effect of unilateral basilar papilla removal on glucose uptake in the 2nd and 3rd order auditory nuclei in the chick's brain stem, nucleus magnocellularis and nucleus laminaris, respectively, was examined with [3H]2-deoxy-D-glucose (2-DG) autoradiography. The tissue was processed according to a thaw-mount techniqu...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90715-5
更新日期:1980-08-25 00:00:00
abstract::These experiments investigated the effect of immediate posttrial administration of peripherally acting DL-4-hydroxyamphetamine on retention of a one-trial inhibitory avoidance response in intact, adrenal medullectomized, sympathectomized, and medullectomized and sympathectomized rats. In intact rats, 0.82 mg/kg of DL-...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90077-3
更新日期:1980-08-18 00:00:00
abstract::A pathway from the pretectal region to the dorsal division of the lateral geniculate body has been studied by autoradiography in adult cats following injection of tritium-labeled amino acids into the meso-diencephalic border zone. The findings suggest that the pretecto-geniculate connection arises in the ipsilateral n...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90861-6
更新日期:1980-08-11 00:00:00
abstract::The ability of neutral red to serve as an internal pH indicator in biological systems was tested in the rat brain after parenteral adminstration of the dye. The injected dye is avidly taken up by the brain cells and is distributed mainly in intracellular organelles. The ratio of optical signals recorded from the froze...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90869-0
更新日期:1980-08-11 00:00:00
abstract::The midbrain raphe nuclei (nucleus raphe dorsalis and nucleus raphe medialis) were destroyed by electrocoaggulation in rats. On the first few days following the lesion, a marked hyperactivity was observed in lesioned animals as well as in shame-operated controls. Between the 5th and 36th days after the lesion, sleep p...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91218-4
更新日期:1980-08-04 00:00:00
abstract::A decline in the magnitude of the summated responses evoked by taste solutions began about 1 h following IXth nerve transection. In 41 IXth nerves transected at different lengths we found a linear relationship between the length of the IXth nerve stump remaining attached to the tongue and the time for the taste respon...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91331-1
更新日期:1980-07-21 00:00:00
abstract::(1) Synaptic transmission was studied in isolated transverse hippocampal slices from guinea pigs. Extracellular evoked potentials were recorded in the region CA1. (2) Changing the normal perfusion solution (containing 2 mM Ca2+) to calcium-free Ringer abolished synaptic transmission which was again restored by adding ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91327-x
更新日期:1980-07-21 00:00:00
abstract::Intracellular recordings of the spontaneous activity were obtained from neurons in long-term cultures from the area of the supraoptic nucleus of rats. The effects of various substances known from in situ studies to cause vasopressin release were analyzed. Application of nicotine or acetylcholine induced a transition f...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90174-2
更新日期:1980-07-14 00:00:00
abstract::Human subjects were asked to perform sinusoidal tracking movements (0.5--3.0 Hz) with their forearms while external torque disturbances were applied at the elbow. The changes in angular position, velocity, and acceleration produced by these disturbances were found to be represented in the reflex changes in EMG activit...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90946-4
更新日期:1980-07-07 00:00:00
abstract::The effects of clonidine (CLO) and phentolamine (PHE) on the sleep-waking cycle in the cat treated with alpha-methyl-p-tyrosine (AMPT) were investigated with continuous 16--24 h polygraphic recordings. For the evaluation of possible cholinergic interactions in the paradoxical sleep (PS) increasing effect of AMPT, an a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90949-x
更新日期:1980-07-07 00:00:00
abstract::Using the rapid Golgi method, the morphology of dendritic spines was quantified in the calyxes of groups of newly emerged, nurse, and forager honeybees. These groups were studied because they represented distinct stages of behavioral development and cumulative experience which, according to recent vertebrate findings,...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91007-0
更新日期:1980-06-16 00:00:00
abstract::The influence of glutamate and aspartate on the time course of decay of excitatory currents at neuromuscular junctions of locust skeletal muscle was examined. Both aspartate (up to 10 mM) and glutamate (up to 0.3 mM) had little influence on the decay time of the synaptic currents, whether measured intracellularly by v...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91020-3
更新日期:1980-06-16 00:00:00
abstract::The duration of the sensitive period of the kitten visual cortex to the effects of monocular deprivation was explored by studies of the behavioral and physiological recovery from extended periods of monocular occlusion imposed from birth, and by examination of the physiological effects of a 3 month period of monocular...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91303-7
更新日期:1980-06-09 00:00:00
abstract::A daily variation of tryptophan hydroxylase (TrH) activity was observed in the raphe dorsalis (RD), raphe centralis (RC) and striatum (St) of 3 inbred strains of mice (BALB/c, C57BL/6, C57BR) and of the reciprocal hybrids obtained from Balb/c and C57BL6. Significant differences of the characteristics of these rhythms ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90322-4
更新日期:1980-06-02 00:00:00